NAD+

An essential coenzyme involved in hundreds of metabolic processes that declines significantly with age. Studied extensively for longevity, energy and cognitive function.

Essential for mitochondrial energy production, DNA repair via PARP enzymes, sirtuin activation for longevity pathways, and cellular stress response.

Every cell in your body needs NAD+ to produce energy. By your 40s your levels may be half what they were in your 20s. Research investigates whether restoring levels can reverse aspects of cellular aging.

• Intracellular NAD+ concentration
• Sirtuin activity
• PARP-mediated DNA repair
• Mitochondrial respiration rate
• Cognitive performance scores
• Metabolic panel markers

• Cellular energy metabolism
• DNA repair
• Cognitive function
• Mitochondrial health
• Longevity pathway activation
• Metabolic health

Discovered in 1906 as a fermentation cofactor, NAD+ returned to prominence through sirtuin and longevity research in the 2000s.

Men and women 35 plus focused on energy, anti-aging, cellular repair, cognitive support and metabolic health.

• Reconstitute with sterile or bacteriostatic water.
• Add diluent slowly and swirl gently.
• Highly light sensitive, protect at all times.
• Store lyophilised at -20C.
• Use reconstituted solution promptly, stability is limited.

• Rapid clearance means administration route matters greatly.
• Flushing and warmth reported with fast administration in human literature.
• Precursor forms behave differently pharmacokinetically.
• Commonly combined with longevity peptides in protocols.