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Epithalon

Also known as Epitalon, Epithalamin

Longevity
EOL-011

Structure

4 amino acids, tetrapeptide

Half-Life

Short

Origin

St Petersburg Institute of Bioregulation and Gerontology

Research

Active preclinical and limited human studies

What it is

A synthetic tetrapeptide derived from the pineal gland, studied as a telomerase activator and one of the most researched longevity compounds available.

Mechanism of Action

Activates the telomerase enzyme to lengthen telomeres, regulates melatonin secretion, provides antioxidant activity and modulates the neuroendocrine system.

In Plain English

Your telomeres are the protective caps on your DNA that shorten every time a cell divides. Epithalon research asks whether activating the enzyme that lengthens them can meaningfully slow cellular aging.

What researchers measure

  • Telomere length
  • Telomerase activity
  • Melatonin secretion rhythm
  • Oxidative stress markers
  • Lifespan in animal cohorts
  • Sleep architecture

Research has studied

  • Telomere lengthening
  • Lifespan extension in animal models
  • Sleep architecture improvement
  • Antioxidant protection
  • Cancer resistance in animal models
  • Hormonal regulation

Origin Story

Developed at the St Petersburg Institute of Bioregulation and Gerontology from pineal gland extract research led by Vladimir Khavinson, with multi-decade Russian follow-up cohorts.

Best suited for

Men and women 40 plus focused on anti-aging, telomere support, sleep improvement, longevity and cellular repair.

Commonly paired with

Usage notes

  • Reconstitute with bacteriostatic or sterile water.
  • Add diluent slowly down the vial wall.
  • Short half-life, protocols typically use short cycles.
  • Store lyophilised at -20C, reconstituted at 4C.
  • Protect from light.

Key considerations

  • Primary evidence base is Russian preclinical and cohort literature.
  • Short half-life, cyclical protocols are standard.
  • Melatonin regulation makes evening timing common.
  • Often stacked with other longevity compounds.

Research-grade Epithalon with full COA documentation is available exclusively through Elite Optimization Labs.

VISIT ELITEOPTIMIZATIONLABS.COM

All information is for educational and research purposes only. Not medical advice. All compounds are for laboratory research use only. Not for human consumption. Consult a licensed healthcare professional.