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Ipamorelin

Also known as Growth hormone secretagogue

Hormonal
EOL-008

Structure

5 amino acids

Half-Life

2 hours

Origin

Novo Nordisk

Research

Active preclinical

What it is

A selective growth hormone secretagogue that stimulates natural GH release without a cortisol or prolactin spike. One of the cleanest GH-stimulating compounds in the research literature.

Mechanism of Action

Selectively binds the ghrelin receptor to stimulate a GH pulse from the pituitary, with no effect on cortisol, prolactin or ACTH at studied concentrations.

In Plain English

Your pituitary releases growth hormone in pulses naturally. Ipamorelin nudges those pulses to be larger and more frequent without the hormonal side effects of less selective compounds. Clean, selective and extensively studied.

What researchers measure

  • Serum GH pulse amplitude
  • IGF-1 levels
  • Cortisol and prolactin baselines
  • Lean mass and body composition
  • Sleep architecture
  • Bone density markers

Research has studied

  • GH optimisation
  • Lean muscle support
  • Fat reduction
  • Sleep quality improvement
  • Anti-aging applications
  • Bone density

Origin Story

Developed by Novo Nordisk as a selective growth hormone secretagogue, distinguished from earlier secretagogues by its lack of cortisol and prolactin elevation.

Best suited for

Men and women 30-65 focused on GH optimisation, lean muscle, fat loss, sleep quality and anti-aging. Typically stacked with CJC-1295.

Commonly paired with

Usage notes

  • Reconstitute with bacteriostatic water down the vial wall.
  • Swirl gently until clear, never shake.
  • Store lyophilised at -20C.
  • Reconstituted solution stable up to 28 days at 4C.
  • Timing near natural GH pulses is common in protocols.

Key considerations

  • Selective for GH release, no cortisol or prolactin spike at studied doses.
  • Short half-life supports pulsatile protocol design.
  • Commonly stacked with a GHRH analogue for amplified pulse.
  • Effects are downstream of natural pituitary function.

Research-grade Ipamorelin with full COA documentation is available exclusively through Elite Optimization Labs.

VISIT ELITEOPTIMIZATIONLABS.COM

All information is for educational and research purposes only. Not medical advice. All compounds are for laboratory research use only. Not for human consumption. Consult a licensed healthcare professional.