BPC-157

A synthetic 15-amino acid pentadecapeptide derived from human gastric juice. One of the most researched healing peptides with a two-decade evidence base spanning tendon, gut, nerve, muscle and bone models.

Modulates growth hormone receptors, promotes angiogenesis via VEGF, activates nitric oxide pathways, and upregulates EGF and FGF growth factors.

The body has a repair switch it flips after injury. BPC-157 research asks whether this compound can flip that switch harder and faster, helping tendons, gut lining, nerves and muscles heal more quickly. It was first discovered in stomach juice, which is one of the stranger origin stories in peptide science.

• IL-6 and TNF-a inflammatory markers
• Tissue regrowth via histology
• VEGF expression
• Tendon tensile strength in transection models
• Gut permeability via FITC-dextran
• Nerve conduction velocity in crush injury models

• Tendon and ligament repair
• Gut barrier integrity and colitis models
• Peripheral nerve regeneration
• Skeletal muscle healing post-crush injury
• Inflammatory cytokine pathway modulation
• Bone healing and joint repair
• Corneal and skin wound closure

First isolated from human gastric juice at the University of Zagreb, Croatia in the early 1990s by Dr Predrag Sikiric. Over 300 independent preclinical studies followed across Croatia, the US and South Korea.

Men and women 25-60, athletes, anyone with gut issues, joint or tendon injuries, and post-surgery recovery.

• Reconstitute with bacteriostatic water.
• Inject diluent slowly down the vial wall.
• Swirl gently, never shake.
• Store lyophilised at -20C.
• Use within 28 days of reconstitution at 4C.

• Short half-life demands precise timing in protocols.
• Compatible with most buffers, pH stable.
• No receptor saturation at studied concentrations.
• Often combined with TB-500 for local and systemic coverage.